Founded in 1975, ICRF is a non-profit organization dedicated to supporting innovative cancer research in Israel and locally here in Montreal. Since its inception, ICRF has provided over $52 million towards cancer research and funded over 2100 cancer research projects both locally, in Montreal, and in Israel.
Together, we can find a cure.
p53: A Key Tumor Suppressor that Prevents Tumor Growth – this is one of the most important discoveries of the 20th century and has inspired cancer researchers around the world. Many cancer researchers now consider the p53 gene to be a possible key to the cure for cancer.
The Philadelphia Chromosome – this is the first genetic link to cancer ever discovered and has led to the development of Gleevec®, a miracle drug for the treatment of chronic myelogynous leukemia. Gleevec® is now used by over 100,000 people worldwide.
Doxil®: A Drug Used in the Treatment of Breast, Ovarian and AIDS-related Cancers. Doxil directs drugs to the diseased tissues only, not to the rest of the patient’s body and releases them slowly. This greatly reduces the side effects normally associated with chemotherapy. The impact of Doxil on the efficacy and safety of treatment of advanced ovarian and breast cancer is already evident in the clinical practice.
RAD 51: A Key Genetic Factor for Higher Breast and Ovarian Cancer Risk – this identifies the likelihood of breast cancer occurring in women who carry the BRCA 2 gene.
Velcade: A Drug for Treating Cancer of the Bone Marrow; Result of Discovery of the Ubiquitin System that Leads to Nobel Prize – ICRF funded Professors Avram Hershko and Aaron Ciechanover won for their discovery of the ubiquitin system. Their research resulted in the development of the drug Velcade®, positioned at the top of Wall Street Journal’s list of the ten “biggest medical Breakthroughs in 2003.” Velcade®, is used for the treatment of multiple myeloma, which is now used by more than 100,000 people in worldwide.
Improved Cancer Treatment – ICRF scientists have discovered improved chemotherapies and advanced techniques in bone marrow transplantation that have improved the survival rates and eased the suffering of many people now battling cancer.